Homer Price lives two miles out of Centerburg, where Route 56 meets 56A, but most of his friends and relatives live in town. They include Aunt Aggy and Uncle Ulysses, the Sheriff and the boys, Miss Terwilliger, Miss Naomi Enders, great-great-great granddaughter of Ezekiel Enders who founded Centerburg and who owned the precious formula for making Cough Syrup and Elixir of Life Compound. While Centerburg is not exactly nosey, precious little happens that the good citizens do not know.

Six episodes in the life of Homer Price including one in which he and his pet skunk capture four bandits and another about a donut machine on the rampage.